BDBM319586 US10174007, Example 5::US10787438, Example 5::US10988463, Example 5::US11634410, Example 5

SMILES C[C@H]1[C@H](O)CN1c1nc(cc(n1)C(F)(F)F)N1C[C@H]2[C@H](CC(O)=O)[C@H]2C1

InChI Key InChIKey=BCRDBPWNFULPMK-LADJIXMOSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 319586   

TargetIsoform A of Ketohexokinase (Peripheral)(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319586(US10174007, Example 5 | US10787438, Example 5 | US...)
Affinity DataIC50:  95.5nMAssay Description:Assay D, was performed using human KHK-A to assess the potency of compounds in inhibiting activity of this enzyme. Compounds were prepared in DMSO as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform A of Ketohexokinase (Peripheral)(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319586(US10174007, Example 5 | US10787438, Example 5 | US...)
Affinity DataIC50:  95.5nMAssay Description:Assay D, was performed using human KHK-A to assess the potency of compounds in inhibiting activity of this enzyme. Compounds were prepared in DMSO as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent